论文部分内容阅读
目的:探讨Ⅲ期肺癌术后早期纤维支气管镜吸痰预防肺部并发症的临床效果。方法:对华中科技大学同济医学院附属同济医院1998年1月～2005年6月行手术治疗的Ⅲ期肺癌的425例临床资料进行回顾性分析,按时间段分为2组:(1)1998年1月～2001年6月为非强化治疗组(93例),年龄(54.6±7.7)岁;(2)2001年6月～2005年6月为强化治疗组(332例),年龄(60.0±6.9)岁。332例患者中173例高危患者术后应用纤维支气管镜床边吸痰,强化呼吸道管理。结果:非强化治疗组术后肺部感染发生率、支气管胸膜瘘发生率、气管切开率和死亡率分别为9.7%、4.3%、6.5%和3.3%;强化治疗组分别为4.2%、1.5%、3.3%和1.2%,2组间比较差异有统计学意义(P<0.05)。结论:术后早期采取纤维支气管镜吸痰是降低肺部并发症和提高手术安全性的有效措施。
Objective: To investigate the clinical effect of bronchoscopy aspiration for prevention of pulmonary complications in stage Ⅲ lung cancer after operation. Methods: The clinical data of 425 cases of stage Ⅲ lung cancer undergoing surgical treatment from January 1998 to June 2005 in Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology were retrospectively analyzed and divided into two groups according to the time period: (1) 1998 The patients in the non-intensive treatment group (n = 93) and the mean age (54.6 ± 7.7) years in the period from January to June 2001 were prospectively enrolled in this study. (2) From June 2001 to June 2005, ± 6.9) years old. Among 332 patients, 173 cases of high-risk patients were treated with fiberoptic bronchoscopy suction side of the bed, to strengthen respiratory tract management. Results: The incidence of postoperative pulmonary infection, the incidence of bronchopleural fistula, tracheostomy and mortality in non-intensive treatment group were 9.7%, 4.3%, 6.5% and 3.3% respectively; in intensive treatment group were 4.2% and 1.5% %, 3.3% and 1.2%, respectively. The difference between the two groups was statistically significant (P <0.05). Conclusion: Early postoperative use of fiberoptic bronchoscopy suction sputum is to reduce pulmonary complications and improve the safety of the operative measures.