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目的:探讨人正常精子形态率对IVF或ICSI治疗结局的影响。方法:观察70周期正常精子形态率对IVF或ICSI后受精率、卵裂率、胚胎冷冻率、种植率、妊娠率及流产率的影响。结果:(1)精子形态异常组,精子的活动率和活动力也显著降低。(2)精子形态正常组IVF受精率、卵裂率显著高于异常组,而IVF的冷冻胚胎率、种植率、妊娠率、流产率及ICSI结局的各项指标两组间均无显著差别。结论:正常精子形态率对IVF受精率、卵裂率有显著影响,而对IVF或ICSI其他治疗结局尚无明显相关。
Objective: To investigate the effect of normal human sperm morphology on IVF or ICSI treatment outcome. Methods: The effects of 70-week normal sperm morphology on IVF or ICSI fertilization rate, cleavage rate, embryo freezing rate, implantation rate, pregnancy rate and abortion rate were observed. Results: (1) In the abnormal sperm group, the sperm motility and activity decreased significantly. (2) IVF fertilization rate and cleavage rate in normal sperm group were significantly higher than those in abnormal group, but there was no significant difference between IVF frozen embryo rate, implantation rate, pregnancy rate, abortion rate and ICSI outcome. CONCLUSIONS: Normal sperm morphological rate has a significant effect on IVF fertilization rate and cleavage rate, but no significant correlation is found between IVF or other ICSI treatment outcomes.