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肾上腺素是心脏停搏、心肺复苏(CPR)时的首选药物。近年发现肾上腺素的常规剂量(每5分钟0.5～1.0mg)在CPR无效时,改用大剂量后则取得满意效果。作者从1990年1月至1991年10月在CPR中开始就用较大剂量的肾上腺素,并取得自主循环恢复的较满意效果。现将收集资料较完整的5例总结如下,并将有关问题进行探讨。
Epinephrine is the drug of choice for cardiac arrest and cardiopulmonary resuscitation (CPR). In recent years, the conventional dose of epinephrine (0.5-1.0 mg every 5 minutes) was found to be satisfactory when switched to high doses after CPR was ineffective. The authors started with larger doses of epinephrine at the beginning of CPR from January 1990 to October 1991 and achieved satisfactory results of spontaneous circulation recovery. We will now collect more complete information on the five cases summarized below, and the relevant issues to be explored.