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目的观察尼莫地平注射液治疗继发性脑室出血的疗效。方法90例继发性脑室出血患者随机分为两组,均常规控制血压、颅压和对症支持治疗,对照组44例应用维生素3.0 g加入生理盐水250 ml中静脉滴注,1次/d,连用2周;治疗组46例,给予尼莫地平注射液50 ml(含尼莫地平10 mg)缓慢静滴,1次/d,连用2周。结果治疗组总有效率及神经功能缺损计分改善情况均较对照组有显著差别(P<0.05),治疗过程中无不良反应发生。结论尼莫地平注射液治疗急性继发性脑室出血临床疗效确切,安全。
Objective To observe the efficacy of nimodipine injection in the treatment of secondary ventricular hemorrhage. Methods Totally 90 patients with secondary intraventricular hemorrhage were randomly divided into two groups: control of blood pressure, intracranial pressure and symptomatic and supportive treatment. In the control group, 44 cases were treated with intravenous drip of vitamin 3.0g and 250 ml normal saline once a day, For 2 weeks; treatment group 46 cases, given nimodipine injection 50 ml (including nimodipine 10 mg) intravenous infusion, once / d, once every 2 weeks. Results The total effective rate and the improvement of neurological deficit scores in the treatment group were significantly different from those in the control group (P <0.05). No adverse reactions occurred during the treatment. Conclusion Nimodipine injection is effective and safe in the treatment of acute secondary intraventricular hemorrhage.