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为了探讨cAMP在电针发热家兔“百会穴”降热效应中的作用,作者选用封闭群大耳白家兔108只,分五组进行实验。实验结果表明:(一)电针发热家兔“百会穴”后,明显降低发热反应和脑脊液cAMP含量增加;(二)电针封闭发热家兔“百会穴”和发热家免“非穴位”后,显示明显的发热反应和脑脊液cAMP含量显著增加;(三)单纯封闭发热家兔“百会穴”,对发热反应和脑脊液cAMP含量增加均无影响。因此,作者推论:电针发热家免“百会穴”抑制发热效应的机理,很可能是和电针“百会穴”中的局部敏感组织(如游离神经末梢)所感受,通过某种方式传入脑内,在脑内又以某种方式抑制cAMP的增多有关,从而抑制调定点上移和出现发热抑制效应。
In order to investigate the role of cAMP in the hypocalcemic effect of electroacupuncture (EA) on “Baihui” rabbit, we selected 108 large white-bellied rabbits, which were divided into five groups. The experimental results showed that: (1) The EAA-induced fever in rabbits “Baihui” significantly reduced the febrile response and the increase of cAMP in cerebrospinal fluid; (2) Electroacupuncture closed the “Baihui” “, Showing significant fever response and a significant increase in cAMP content in cerebrospinal fluid; (C) simply blocking the fever” Baihui “rabbits, fever and cerebrospinal fluid cAMP content increased no effect. Therefore, the authors conclude that the mechanism by which electroacupuncture at ”Baihui acupoint“ inhibits fever is likely to be related to the local sensitive tissues (such as free nerve endings) in electro-acupuncture ”Baihui", by some means Into the brain, in the brain and somehow inhibit the increase in cAMP, thereby inhibiting the transfer point of regulation and the emergence of fever inhibitory effect.