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〔答〕痢特灵又称呋喃唑酮,主要用于治疗细菌性肠道疾病,如菌痢、肠炎等。近年来报道对胃、十二指肠溃疡、伤寒、泌尿道感染等也有一定的疗效,应用范围较广。痢特灵是一种单胺氧化酶抑制剂,口服后在肠道细菌作用下,生成2-羟乙胺的代谢物,能抑制心、肝、脑等组织内的单胺氧化酶,使5-羟色胺、多巴胺及去甲肾上腺素等神经传导介质不被氧化破坏,蓄积在组织中,从而引起恶心、呕吐、头晕、头痛等症状。如饮酒,机体对其敏感性增高,会引起严重的醉酒,除上述症状加重外,还会表现皮肤发红,眼睛布满血丝、心慌、气短、头晕眼花,头剧烈跳
〔A〕 Furazolidone, also known as furazolidone, is mainly used for the treatment of bacterial intestinal diseases, such as bacillary dysentery, enteritis and so on. In recent years, reports on the stomach, duodenal ulcer, typhoid, urinary tract infections, also have a certain effect, a wide range of applications. Furazolidone is a monoamine oxidase inhibitor, after oral administration in the intestinal bacteria to produce metabolites of 2-hydroxyethylamine, can inhibit the heart, liver, brain and other tissues of monoamine oxidase, 5-HT, dopamine and to Nerve conduction medium such as norepinephrine is not oxidative damage, accumulation in the organization, causing nausea, vomiting, dizziness, headache and other symptoms. Such as drinking, the body’s increased sensitivity to it will cause serious drunkenness, in addition to the above symptoms, but also the performance of the skin redness, eyes full of bloodshot eyes, palpitation, shortness of breath, dizziness, head fierce jump