论文部分内容阅读
目的 观察诺维本 (NVB) +吡喃阿霉素 (THP)联合治疗晚期乳腺癌疗效。方法 NVB+THP联合治疗 31例晚期乳腺癌 ,均为女性 ,其中Ⅲ期 18例 ,Ⅳ期 13例。结果 本组 31例完全缓解 (CR) 3例 ,部分缓解 (PR) 16例 ,有效率为 61 3%。主要毒付反应 ,是骨髓抑制或静脉炎 ,白细胞下降为 93 2 %,其中Ⅲ、Ⅳ度为 50 2 %,静脉炎发生率为 4 2 0 %。结论 NVB +THP联合治疗乳腺癌 ,有效率较高 ,但骨髓抑制发生率高 ,必须引起重视。
Objective To observe the efficacy of combination of NVB and THP in the treatment of advanced breast cancer. Methods 31 patients with advanced breast cancer were treated with NVB + THP, all of whom were female, including 18 cases of stage Ⅲ and 13 cases of stage Ⅳ. Results 31 cases of complete remission (CR) in 3 cases, partial response (PR) in 16 cases, the effective rate was 61 3%. The main drug-induced reaction was myelosuppression or phlebitis. The leukopenia was 93.2%. The grade Ⅲ and Ⅳ were 50.2% and the phlebitis was 42.0%. Conclusion NVB + THP combined treatment of breast cancer, high efficiency, but the high incidence of bone marrow suppression, we must pay attention.