论文部分内容阅读
目的综述与肝脏再生有关的调控因子的研究进展。方法收集近年来与肝脏再生有关的调控因子方面的文献并作综述。结果随着近年来对各种与肝脏再生有关的调控因子研究的进一步深入,可能为肝脏相关的疾病带来更多的治疗手段。调控因子在肝脏再生过程中起着非常重要的作用,其中细胞生长因子对肝细胞增殖起了重要的作用,如适量表达的TNF-α和IL-6启动肝细胞增殖,HGF、TGF-α、EGF、ALR、FS等在促进肝细胞增殖中起重要作用,而TGF-β和IL-1则是肝细胞增殖的终止物质。结论通过加强与肝脏再生有关的调控因子的研究,可能为肝脏相关疾病的治疗提供新思路。
Objective To summarize the research progress of regulators related to liver regeneration. Methods Collecting and reviewing the regulatory factors related to liver regeneration in recent years. The results With the further researches on various regulators related to liver regeneration in recent years, it may bring more treatment for liver-related diseases. Regulatory factors play a very important role in the process of liver regeneration. Among them, cell growth factor plays an important role in the proliferation of hepatocytes. For example, proper amount of TNF-α and IL-6 can initiate hepatocyte proliferation, HGF, TGF-α, EGF, ALR, FS and so on play an important role in promoting the proliferation of hepatocytes, while TGF-β and IL-1 are the termination substances of hepatocyte proliferation. Conclusions By strengthening the regulation of regulators related to liver regeneration, it may provide new ideas for the treatment of liver-related diseases.