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为了探讨肝包虫病患者血清白细胞介素6(IL-6)和肿瘤坏死因子a(TNF-a)水平及其与肝包虫病的关系,应用ELISA法检查42例正常人、27例肝包虫病人血清TNF-a水平,其中20例病人同时检测IL-6水平,结果显示肝包虫病患者血清IL-67水平为0.1626±0.100ng/ml,显著高于正常人0.0191±0.0168ng/ml(P<0.001),TNF-a水平为8.9946±5.3112ng/ml,也显著高于正常人2.2967±0.9317ng/ml(P<0.01),作者认为对IL-6和TNF-a水平的检测可作为肝包虫病患者免疫功能检查指标之一,对肝包虫病的发病机制并对疾病的严重程度、疗效及预后的判断具有重要意义。
To investigate the relationship between serum interleukin 6 (IL-6), tumor necrosis factor a (TNF-a) and hepatic hydatid disease in patients with hepatic hydatid disease, 42 cases of normal and 27 cases of liver Serum levels of TNF-a in hydatid disease patients, including 20 patients with simultaneous detection of IL-6 levels, the results showed that hepatic hydatid disease serum IL-67 levels 0.1626 ± 0.100ng / ml, significantly higher than the normal 0 (P <0.001). The level of TNF-a was 8.9946 ± 5.3112ng / ml, which was also significantly higher than that of normal people (2.2967 ± 0.9317ng / ml) (P <0. 0191 ± 0.0168ng / .01), the authors believe that the detection of IL-6 and TNF-a levels can be used as indicators of immune function in patients with hepatic hydatid disease, the pathogenesis of hepatic hydatid disease and the severity of the disease, efficacy and prognosis Judgment is of great significance.