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目的研究旅英华人和当地白人血管内皮功能有无差异。方法选取年龄、性别相似的旅英华人和当地白人各40名(男女各20名),检测体质量、身高、腰围、血压、血脂、血糖、血流介导的内皮依赖性血管舒张功能(FMD)等,比较两组检测结果,并分析心血管危险因素、种族与FMD的相关性。结果旅英华人的舒张压、FMD较当地白人高[舒张压(80.2±9.1)比(75.1±11.3)mmHg;FMD(6.76±2.95)%比(5.52±2.13)%,均P<0.05],体质量、腰围、体质量指数(BMI)较当地白人低[体质量(65.4±10.9)比(74.3±12.4)kg;腰围(82.2±8.1)比(89.4±10.9)cm;BMI(23.5±2.3)比(24.8±3.2)kg/m2;均P<0.05]。旅英华人饮食以中餐为主,占80%,白人则全以西餐为主。种族因素、饮食习惯与FMD相关(偏回归系数分别为-1.232、1.555,均P<0.05)。结论旅英华人的血管内皮功能优于当地白人,可能与种族因素、饮食习惯相关。
Objective To study whether there is any difference in the vascular endothelial function between British Chinese and local white people. Methods Forty Twenty British and Caucasian whites of the same age and sex were randomly selected. Twenty individuals, 20 males and 20 females, were enrolled in this study. Body weight, height, waist circumference, blood pressure, blood lipid, blood glucose, blood flow-mediated endothelium-dependent vasodilatation FMD) and so on. The test results of two groups were compared, and the correlation between cardiovascular risk factors and race and FMD was analyzed. Results The diastolic blood pressure of FMD patients in China was significantly higher than that of the local white patients (80.2 ± 9.1 vs 75.1 ± 11.3 mmHg, 6.76 ± 2.95% vs 5.52 ± 2.13%, P <0.05, respectively) Body mass, waist circumference and body mass index (BMI) were significantly lower than those in the native white [body mass (65.4 ± 10.9) vs (74.3 ± 12.4) kg; waist circumference (82.2 ± 8.1) 2.3) than (24.8 ± 3.2) kg / m2; all P <0.05]. The British diet mainly focuses on Chinese food, accounting for 80% of the total, whereas white people mainly rely on Western food. Racial factors and eating habits were related to FMD (partial regression coefficients were -1.232 and 1.555 respectively, all P <0.05). CONCLUSIONS: British Chinese have better vascular endothelial function than native whites and may be related to ethnic factors and eating habits.