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利用 HCG 羧基端肽的抗血清已能测出在正常人的许多组织和体液中存在少量 HCG 或 HCG 样物质。正常人尿样中约含25～65ng/天的 HCG 样物质。人垂体中 HCG 样物质的生物活性、理化及免疫学特性均与高度纯化的 HCG 制剂难于区分。为观察 HCG 样物质的分泌型式及其调节,作者研究了不同年龄妇女及用避孕措施妇女 HCG 样物质的排出形式。选择9例25～43岁的正常妇女进行研究,用避孕措施者不限制房事,未用避孕措施者完全避免房事。从月经第一天开始,每天收集尿样,用双抗体
Antisera using HCG carboxy-terminal peptides have been tested for the presence of small amounts of HCG or HCG-like material in many tissues and body fluids of normal humans. Normal human urine samples contain approximately 25-65 ng / day of HCG-like material. The biological activity, physicochemical and immunological properties of human pituitary HCG-like substances are indistinguishable from those of highly purified HCG preparations. In order to observe the secretion patterns of HCG-like substances and their regulation, the authors studied the forms of HCG-like excretion of women of different ages and women using contraception. Nine normal women aged 25-43 years were selected for study. All those using contraceptives were not restricted, and those who did not use contraception were completely free of sexual intercourse. From the first day of menstruation, urine samples are collected daily and diabodies