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为了探讨木尘与癌症的关系，我们对某木综厂进行了回顾性队列研究，木尘组为该厂接触木尘者２３６２（男１７０７，女６５５）人，３３６７９人年，观察期１５年（１９７８．１．１．～１９９２．１２．３１．），非木尘组为本地某煤矿职工２５８７人，５４０４０人年，观察期２１年（１９７２．１．１．～１９９２．１２．３１．），并与当地居民的死亡率进行了比较。队列中全部癌症病人均为Ｉ～Ⅱ级诊断，木尘接触工人前３位的癌症分别是肺癌（３５．１％）、肝癌（１８．２％）和食道癌（１５．６％）。与非木尘组比较，木尘接触职工全癌、肺癌、肠癌、食道癌的标化死亡率分别为２４２．５２、７４．６２、４３．７８和４２．８２／１０万，ＲＲ分别为１．９８、４．０８、３．２３和２．８８，均有高度显著性差异（Ｐ＜０．０１）。全癌、肺癌、肠癌和白血病的ＳＭＲ分别为１５４．８、２１８．６、２８４．８和３５２．７（Ｐ＜０．０５或Ｐ＜０．０１）。提示木尘可能与肺癌、肠癌、食道癌、肝癌和白血病有一定关系。
In order to explore the relationship between wood dust and cancer, we conducted a retrospective cohort study on a wood integrated plant. The wood dust group had 2362 (male 1707, female 655) people exposed to wood dust, with 33,679 person-years and observation period of 15 years. (1978.1.1. ~ 1992.12.31.), non-wood dust group is a local coal mine staff of 2587 people, 54040 people, observation period of 21 years (1972.1.1. ~ 1992.12.31. ), And compared with the mortality of local residents. All cancer patients in the cohort were diagnosed in grades I to II. The top 3 cancers that exposed wood dust to workers were lung cancer (35.1%), liver cancer (18.2%), and esophageal cancer (15.6%). Compared with the non-wood dust group, the standard death rates of wood dust exposure to workers’ cancer, lung cancer, colon cancer, and esophageal cancer were 242.52, 74.62, 43.78, and 42.82/100 000, respectively. 1.98, 4.08, 3.23, and 2.88 were highly significant differences (P<0.01). The SMR of total cancer, lung cancer, colon cancer, and leukemia was 154.8, 218.6, 284.8, and 352.7, respectively (P<0.05 or P<0.01). Tip wood dust may have a certain relationship with lung cancer, colorectal cancer, esophageal cancer, liver cancer and leukemia.