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目的探讨男性不育症患者精液支原体感染及药敏情况。方法应用法国生物梅里埃Biomerieux公司Myco-plsasma IST试剂盒,按说明书进行操作,对男性不育症患者精液进行支原体检测,同时测定其对抗菌药物的耐药性。结果 262份精液标本中支原体感染率为38.93%(102例),其中单纯解脲脲原体(U u)感染率为30.15%(79例),单纯人型支原体(M h)感染率为3.05%(8例),U u+M h混合感染率为5.73%(15例)。9种抗菌药物药敏试验结果显示耐药率最高的是环丙沙星和氧氟沙星,其耐药率超过70%。结论男性不育症患者精液支原体的感染已相当普遍,治疗支原体感染宜选用大环内酯类、四环素类药物。
Objective To investigate the infection and drug susceptibility of Mycoplasma genitalium in male infertility patients. Methods The Myco-plsasma IST kit from Biomerieux, France was used to perform mycoplasma test on semen of male infertility patients according to the instruction manual and to determine its resistance to antibiotics. Results The infection rate of mycoplasma in 262 semen samples was 38.93% (102 cases). The infection rates of Uu were only 30.15% (79 cases) and those of Mycoplasma hominis (M h) were 3.05 % (8 cases), U u + M h mixed infection rate was 5.73% (15 cases). Nine kinds of antimicrobial drug susceptibility test results show that the highest rate of resistance is ciprofloxacin and ofloxacin, the resistance rate of more than 70%. Conclusion The infection of Mycoplasma hyopneumoniae in male infertility patients has been quite common. The treatment of mycoplasma infection should use macrolides and tetracyclines.