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目的:分析我院抗菌药物不良反应的特点及规律,为临床合理用药提供依据。方法:采用回顾性研究方法,分类统计我院2012年1月—2013年12月收集的抗菌药物不良反应报告,分别从患儿的性别、年龄、药品种类、不良反应累计的系统和器官及主要临床表现等方面进行统计、分析、评价。结果:51例抗菌药物不良反应中,(0~3)岁患儿比例最高占80.39%;头孢菌素类引起的不良反应例数最多,为27例,占52.94%;不良反应累积的系统和器官主要为皮肤附件,为31例,占60.78%。结论:临床给儿童使用抗菌药物,需关注不良反应的发生。
Objective: To analyze the characteristics and rules of adverse reactions of antimicrobial agents in our hospital and provide the basis for clinical rational drug use. Methods: A retrospective study was conducted to classify the adverse reactions of antimicrobial agents collected in our hospital from January 2012 to December 2013 according to their sex, age, type of drugs, adverse reactions, and the main Clinical performance and other aspects of statistics, analysis, evaluation. Results: Among the 51 cases of antibiotics, the highest proportion of children (0-3 years) accounted for 80.39%. The number of adverse reactions caused by cephalosporins was the highest (27 cases, 52.94%). The cumulative number of adverse reactions was The main organ of the skin attachment, 31 cases, accounting for 60.78%. Conclusion: Clinical use of antibiotics in children needs to pay attention to the occurrence of adverse reactions.