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本文采用放射免疫法对３１例老年非溃疡性消化不良（ＮＵＤ）患者和２０例对照者在空腹状态下进行了血清胃泌素、血浆胃动素及生长抑素的测定。结果显示：老年人ＮＵＤ组胃泌素浓度为８５．７２±２２．０３ｐｇ／ｍｌ，较对照组的９０．４２±１５．０６ｐｇ／ｍｌ，差异无显著性（Ｐ＞０．０５）；胃动素浓度为４２７．７４±９５．８５ｐｇ／ｍｌ，较对照组的５４５．７３±１１５．８０ｐｇ／ｍｌ，差异有显著性（Ｐ＜０．０５）；生长抑素浓度为６９．４７±１８．７５ｐｇ／ｍｌ，较对照组的５４．７６±１３．３２ｐｇ／ｍｌ，差异有显著性（Ｐ＜０．０５）。提示胃动素，生长抑素在老年人ＮＵＤ发病机理中起一定作用，而胃泌素则无明显作用。
In this paper, 31 cases of elderly non-ulcer dyspepsia (NUD) patients and 20 controls were measured by radioimmunoassay in fasting serum gastrin, plasma motilin and somatostatin. The results showed that the concentration of gastrin in the elderly NUD group was 85.72 ± 22.03pg / ml, which was significantly higher than that in the control group (90.42 ± 15.06pg / ml) (P> 0.05) The concentration was 427.74 ± 95.85pg / ml, which was significantly higher than that of the control group (545.73 ± 115.80pg / ml) (P <0.05). Somatostatin concentration was 69.47 ± 18. 75pg / ml, compared with the control group 54.76 ± 13.32pg / ml, the difference was significant (P <0.05). Tip motilin, somatostatin in the pathogenesis of NUD in the elderly play a role, while gastrin has no significant effect.