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目的 比较地氟醚对血液动力学和儿茶酚胺的影响。方法 择期手术病人３０ 例（ＡＳＡⅠ～Ⅱ） ，随机分为地氟醚（１５ 例）、异氟醚（１５ 例）两组。不用术前药。气管插管后观察不同ＭＡＣ时地氟醚和异氟醚对ＭＡＰ、ＨＲ和血中儿茶酚胺浓度的影响。结果 在地氟醚组达１－５ ＭＡＣ后呈现２～４ ｍｉｎ 的血压增高和心率增快，且儿茶酚胺增高。结论 快速增加地氟醚浓度至１－５ＭＡＣ可出现交感兴奋作用，而异氟醚没有此作用。
Objective To compare the effects of desflurane on hemodynamics and catecholamines. Methods Thirty patients (ASA Ⅰ ~ Ⅱ) undergoing elective surgery were randomly divided into two groups: desflurane (15 cases) and isoflurane (15 cases). No preoperative medicine. The effects of desflurane and isoflurane on MAP, HR and catecholamine levels in blood after tracheal intubation were observed. RESULTS: After desflurane group 1-5 MAC, blood pressure increased and heart rate increased from 2 to 4 minutes, and catecholamines increased. Conclusion The rapid increase of desflurane concentration to 1-5MAC sympathetic excitement may occur, while isoflurane does not have this effect.