论文部分内容阅读
目的评估磁共振弥散加权成像(DWI)在预估直肠癌侵袭性和预后中的价值。方法测量直肠癌肿瘤的平均ADC值并将其与不同预后因素进行统计学比较。直肠癌预后因素包括：术前CEA、肿瘤肠壁外侵犯深度、肿瘤T、N分期、直肠系膜筋膜是否侵犯、肿瘤分化程度和肠外神经血管是否侵犯。结果术前CEA、肿瘤肠壁外侵犯深度，病理N分期，直肠系膜筋膜是否侵犯和肿瘤分化程度的平均ADC值差异具有统计学意义。病理T分期和肠外神经血管是否侵犯的平均ADC值差异无统计学意义。结论 ADC值可作为评估直肠癌侵袭性和预后的一个无创性生物学指标。“,”Objective Assess the value of dif usion-weighted MRI (DWI) as a potential noninvasive marker of tumor aggressiveness in rectal cancer. Methods Mean tumor ADC was measured and compared between subgroups based on pretreatment CEA levels, extramural depth (EMD) of tumor invasion, T-stage, N-stage, mesorectal fascia (MRF)status, dif erentiation grade and extramural neurovascular invasion. Results Mean tumor ADC values dif er between CEA, EMD, N-stage, MRF and histological dif erentiation grades subgroup. There was no significant dif erence in mean ADC values between T-stage and extramural neurovascular subgroup. Conclusion ADC value has the potential to become an imaging biomarker of rectal tumor aggressiveness profile.