Preparation of new technetium-99m NNS/X complexes and selection for brain imaging agent

• 作 者: HE Qiange CHEN Xiangji MIAO Yu
• 机 构: ChemistryDepartment
• 出 处: 中国科学：化学英文版
• 发表日期: 2004年6期
• 关键词: 99mTc BRAIN PERFUSION IMAGING agent MPBDA MPTDA MPDAA. 99mTc brain perfusion
• 基金项目: This work was supported by the National Natural Science Foundation of China (Grant No. 29731020).

Based on excellent experiment results of 99mTcO-MPBDA-Cl, two new ligands MPTDA and MPDAA are synthesized. Then series of 99mTcO3+ complexes are prepared through adding different halide anions, followed by tests of physical chemistry qualities and biodist