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目的探讨双水平气道正压通气(BIPAP)呼吸机无创通气治疗慢性阻塞性肺疾病(COPD)并Ⅱ型呼吸衰竭的疗效。方法将COPD合并Ⅱ型呼吸衰竭患者60例随机分成(观察组和对照组)。对照组30例用鼻导管持续低流量吸氧,观察组30例加用BiPAP呼吸机通气治疗,观察治疗前后临床症状、动脉血气等指标的变化。结果观察组经BiPAP呼吸机治疗后患者血氧饱和度及血气分析等指标改善明显优于对照组(P<0.05)。结论无创机械通气治疗能够显著改善COPD合并Ⅱ型呼吸衰竭患者动脉血气指标和呼吸状况。
Objective To investigate the efficacy of noninvasive ventilation with bipolar positive airway pressure (BIPAP) ventilator in treating chronic obstructive pulmonary disease (COPD) and type Ⅱ respiratory failure. Methods Sixty COPD patients with type Ⅱ respiratory failure were randomly divided into observation group and control group. Thirty patients in the control group were treated with nasal cannula for continuous low-flow oxygen inhalation. In the observation group, 30 patients were treated with BiPAP ventilator ventilation. Changes of clinical symptoms and arterial blood gas were observed before and after treatment. Results The oxygen saturation and blood gas analysis of patients in the observation group after BiPAP ventilator treatment were significantly better than those in the control group (P <0.05). Conclusion Non-invasive mechanical ventilation can significantly improve arterial blood gas index and respiratory status in COPD patients with type Ⅱ respiratory failure.