论文部分内容阅读
蚊虫是重要的虫媒疾病传播媒介,可传播多种疾病,如疟疾、登革热等,严重危害人类健康。媒介蚊虫的防治是控制此类传染病的重要措施。蚊虫依赖天然免疫系统抵御疟原虫、真菌、病毒等外源病原体的侵染。蚊虫免疫主要分为体液免疫和细胞免疫。补体识别激活系统、免疫信号通路、黑化反应和活性氧等途径均参与了对病原体的免疫反应。现就媒介蚊虫抵御疟原虫和真菌等病原体免疫应答机制的最新进展进行综述。这将为发展新的蚊虫控制策略提供理论支持。
Mosquitoes are important vectors for transmitting vector diseases and can spread various diseases such as malaria and dengue fever, which seriously endanger human health. Prevention and control of vector mosquitoes is an important measure to control such infectious diseases. Mosquitoes rely on the innate immune system against infections by foreign pathogens such as Plasmodium, fungi, and viruses. Mosquito immunity is divided into humoral and cellular immunity. Complement recognition activation system, immune signaling pathway, melanization and reactive oxygen species are involved in the pathogen immune response. The recent progress of vector mosquitoes against the immune response mechanisms of pathogens such as Plasmodium and fungi is reviewed. This will provide theoretical support for the development of new mosquito control strategies.