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目的:评价中药生柿楴汤与维生素B_1(VB_1)内关穴穴位注射对肿瘤患者顽固性呃逆的疗效。方法:选取2012年8月—2013年8月间收治的肿瘤顽固性呃逆患者80例,将其随机分为对照组和观察组,每组40例;对照组给予口服中药生柿楴汤治疗,观察组患者在对照组基础上再给予VB_1内关穴位注射治疗,评价两组患者治疗7 d后的总有效率,以及治疗后首次呃逆消失时间和再发作时间。结果:观察组患者治疗后的总有效率为87.50%高于对照组为85.00%(P>0.05);观察组患者治疗后首次呃逆消失时间为(0.386±0.023)h短于对照组为(0.523±0.052)h(P<0.05),呃逆中止首次再发作时间为(6.31±1.39)h优于对照组为(4.38±1.34)h(P<0.05)。结论:采用中药生柿楴汤与穴位注射VB_1治疗肿瘤患者顽固性呃逆的疗效与单用中药生柿楴汤的疗效相当,但联合治疗起效更快,药效长。
OBJECTIVE: To evaluate the curative effect of intragastric injection of Chinese medicine Shengshu Tang and Vitamin B_1 (VB_1) on refractory hiccup in cancer patients. Methods: Eighty patients with intractable hiccup tumors were enrolled from August 2012 to August 2013. They were randomly divided into control group and observation group, 40 cases in each group. The control group was treated with the traditional Chinese medicine of persimmon soup, The patients in the observation group were given VB 1 injection of Neiguan acupoint on the basis of the control group to evaluate the total effective rate of the two groups after 7 days of treatment and the disappearance time and recurrence time of the first hiccup after treatment. Results: The total effective rate of observation group was 87.50% after treatment and 85.00% of control group (P> 0.05). The disappearance time of the first hiccup in observation group was (0.386 ± 0.023) h after treatment, ± 0.052) h (P <0.05). The duration of the first recurrent attack was (6.31 ± 1.39) h hiccup compared with that of the control group (4.38 ± 1.34) h (P <0.05). Conclusion: The curative effect of refractory hiccup with Chinese traditional medicine persimmon soup and acupoint injection of VB_1 is similar to that of traditional Chinese medicine persimmon soup alone, but the combination therapy has faster onset and longer efficacy.