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缺氧缺血性脑病(Hypoxia ischemic encephalopathy以下称HIE)是围产期新生儿因缺氧引起的脑部病变,主要由宫内窒息、新生儿窒息脑缺氧所致,多见于足月儿,是围产期足月儿脑损伤的最常见原因,少数可发生在其他原因引起的脑损害。轻者通常预后良好,严重者在新生儿早期即死亡并可造成不可逆的脑损害,产生永久性神经功能缺陷,如智能低下、脑性瘫痪、痉挛、癫痫和共济失调等。新生儿窒息的本质是缺氧,轻症、早期窒息由于海豹潜水反射机制的存在产生血液重新分布、心、脑等主要脏
Hypoxia ischemic encephalopathy (hereinafter referred to as HIE) is perinatal neonatal hypoxia-induced brain lesions, mainly due to intrauterine asphyxia, neonatal asphyxia cerebral hypoxia caused more common in full-term children, Perinatal term brain injury is the most common cause, a few may occur in other causes of brain damage. Light is usually a good prognosis, severe cases of death in the early neonatal period and can cause irreversible brain damage, resulting in permanent neurological deficits, such as mental retardation, cerebral palsy, spasticity, epilepsy and ataxia. The essence of neonatal asphyxia is hypoxia, mild disease, early asphyxia due to the presence of seal diving reflection mechanism to produce blood redistribution, heart, brain and other major dirty