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To determine whether the concentration of hCG in cervical fluid can predict miscarriage during early pregnancy. Design: Prospective clinical study. Setting: University hospital. Patient(s): Ninety-nine women with singleton pregnancies, 17 of whom suffered a miscarriage. Intervention(s): None. Main Outcome Measure(s): Miscarriage and the cervical fluid/- serum hCG concentration ratio. Result(s): With a cutoff value of 1.0, the sensitivity, specificity, and positive and negative predictive values of the cervical fluid/serum hCG concentration ratio for predicting miscarriage were 88.2% , 94.9% , 83.3% , and 96.6% , respectively. Conclusion(s): The cervical fluid/serum hCG concentration ratio might be a useful predictor of miscarriage during early pregnancy.
Setting: University hospital. Intervention (s): Ninety-nine women with singleton pregnancies, 17 of whom suffered a miscarriage. Intervention (s) Main Outcome Measure (s): Miscarriage and the cervical fluid / - serum hCG concentration ratio. Result (s): With a cutoff value of 1.0, the sensitivity, specificity, and positive and negative predictive values of the cervical The serum / serum hCG concentration ratio for predicting miscarriage were 88.2%, 94.9%, 83.3%, and 96.6%, respectively. Conclusion (s): The cervical fluid / serum hCG concentration ratio might be a useful predictor of miscarriage during early pregnancy.