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高血糖素(胰高血糖素Glucagon)是胰岛α-细胞分泌的一种激素。这种α-细胞与胰岛分泌胰岛素的β-细胞很靠近,在形态学上形成一对对的分泌细胞,这些成对的细胞同时分泌着作用相反的两种激素。自从发现糖尿病的病因主要是缺乏胰岛素后,胰岛素制剂即广泛应用于糖尿病的治疗,获得了良好的治疗效果。但在早期从胰脏提取胰岛素时,由于技术水平的关系,其中混有高血糖素,尔后因提纯技术的进步,高血糖素才被分离出来,因为它有升高血糖的作用称为高血糖素。后来在胃、肠里也发现了这种相同的生物活性物质,由空肠、十二指肠和胃壁细胞分泌,称为胃肠道高血糖素。高血糖素的发现,时间虽已有了50年,但由于
Glucagon (Glucagon) is a hormone secreted by pancreatic α-cells. The a-cells are very close to the islet-secreting insulin beta-cells, morphologically forming a pair of secreting cells that simultaneously secrete two hormones that act in opposite directions. Since the main cause of diabetes found in the lack of insulin, insulin preparations that are widely used in the treatment of diabetes, get a good therapeutic effect. But in the early extraction of insulin from the pancreas, because of the level of technology, which mixed with glucagon, and later because of purification technology, glucagon was isolated because it has the effect of raising blood sugar called hyperglycemia Prime Later in the stomach, intestines also found this same bioactive substances, secreted by the jejunum, duodenum and parietal cells, called gastrointestinal glucagon. The discovery of glucagon, although the time has been 50 years, but due