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目的观察纤维支气管镜下局部给药与雾化吸入治疗对支气管结核的临床疗效,探讨纤维支气管镜治疗该病的临床优势。方法将收治的28例患者行纤维支气管镜下局部给药作为观察组。取同期采取雾化吸入治疗的30例患者作为对照组。对比两组疗效及副反应。结果连续用药8w后,观察组与对照组治疗总有效率分别为92.86%、70.00%,观察组明显优于对照组(P<0.05)。观察组有1例出现病变黏膜出血,经纤维支气管镜喷洒稀释去甲肾上腺素后病症消除,两组均未见发热、气胸、继发肺部感染等不良症状。结论给予支气管结核患者在全身化疗的基础上行纤维支气管镜下局部给药,疗效显著且无明显副作用,值得在临床推广。
Objective To observe the clinical effect of local administration and atomization inhalation therapy on bronchial tuberculosis under fiberoptic bronchoscopy, and to explore the clinical advantages of bronchoscopy in the treatment of bronchial tuberculosis. Methods Twenty-eight patients underwent local bronchoscopy as the observation group. Take the same period to take inhalation treatment of 30 patients as a control group. Compare two groups of curative effect and side reaction. Results After continuous administration for 8 weeks, the total effective rates of the observation group and the control group were 92.86% and 70.00%, respectively. The observation group was significantly better than the control group (P <0.05). In the observation group, 1 patient had lesions mucosal hemorrhage, and the symptoms were eliminated after the noradrenaline was diluted by bronchoscopy. No adverse symptoms such as fever, pneumothorax and secondary pulmonary infection were found in both groups. Conclusion Bronchial tuberculosis patients under local chemotherapy on the basis of local bronchoscopic administration, significant effect and no significant side effects, it is worth in the clinical promotion.