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同步检测30名慢性乙肝患者和15名正常成人的淋巴细胞转化率(LTT)和淋巴细胞内环一磷酸腺苷(cAMP)含量,结果显示慢性乙肝患者的LTT较正常人降低,其(?)±s分别为80.58±22.43和107.91±42.15(P<0.05)。而慢性乙肝患者的cAMP较正常人显著升高,分别为3.34±0.93和2.34±0.55(P<0.05)。慢性乙肝患者LTT和CAMP之间呈负相关关系r=-0.39,P<0.05,而正常对照组两者的相关关系无显著性。检测慢性乙肝患者的LTT和cAMP均有助于了解其细胞免疫状态。
Simultaneous detection of LTT and cAMP in 30 chronic hepatitis B patients and 15 normal adults showed that patients with chronic hepatitis B had lower LTT than normal controls ± s were 80.58 ± 22.43 and 107.91 ± 42.15, respectively (P <0.05). The chronic hepatitis B patients cAMP significantly higher than normal, were 3.34 ± 0.93 and 2.34 ± 0.55 (P <0.05). There was a negative correlation between LTT and CAMP in patients with chronic hepatitis B (r = -0.39, P <0.05), but there was no significant difference between the two groups in the control group. Detection of chronic hepatitis B patients with LTT and cAMP are helpful to understand the cellular immune status.