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目的:分析2015年中成药使用情况,为临床合理使用提供参考。方法:从门急诊777 242张处方中随机抽取493张,分析门急诊处方中成药的合理使用情况,分析2015年全院中成药相关性药物不良反应(Adverse drug reaction,ADR)。结果:抽取的493张门急诊处方中,开具中成药的处方为239张占48.48%,中成药处方中口服制剂占69.00%,静脉用药占27.6%;不合理处方总数为76张,其中中成药使用不合理处方占不合理处方总数15%;2015年医院ADR为190例,其中中成药相关性ADR占9.47%,与抗菌药物联合使用的占7.89%。结论:医院临床中成药尤其是中药注射剂的使用比例较高,致ADRs的发生率上升,应加强对中成药使用的行政干预,确保患儿用药安全有效。
Objective: To analyze the use of proprietary Chinese medicines in 2015 and provide a reference for clinical rational use. Methods: A total of 493 out of 777 outpatient and emergency department prescriptions were analyzed. The rational use of proprietary Chinese medicines in outpatient and emergency department was analyzed. Adverse drug reaction (ADR) was analyzed in 2015. Results: Among the 493 outpatient and emergency department prescriptions, 239 prescriptions accounted for 48.48%, 69.00% were prescriptions for proprietary Chinese medicines, and 27.6% were for intravenous medicines. The total number of unreasonable prescriptions was 76, of which proprietary Chinese medicines The use of unreasonable prescriptions accounted for 15% of the total number of unreasonable prescriptions; in 2015, the hospital ADR was 190 cases, of which proprietary Chinese medicine-related ADR accounted for 9.47% and antimicrobial drugs accounted for 7.89%. Conclusion: The clinical use of proprietary Chinese medicines, especially traditional Chinese medicine injections, is high, leading to an increased incidence of ADRs. Administrative interventions for the use of proprietary Chinese medicines should be strengthened to ensure safe and effective drug use in children.