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作者研究了长期使用Cu-IUD妇女的血清铜含量以确定长期使用Cu-IUD是否伴有血清铜含量的任何改变甚或引起铜中毒。研究包括纵横两方面,横的研究是比较148名未用任何节育方法的妇女(对照组)与95名使用Lippes Loop 6～48个月的妇女及107名使用Cu-T_(200)6～48个月的妇女血清铜含量的测定以确定使用Cu-IUD者与未用者血清铜含量有无差异。纵的研究包括7名未用任何节育方法的妇女及17名置Cu-IUD的妇女,每3个月测定1次血清铜含量直至24个月以上,以追踪研究置Cu-IUD和未置Cu-IUD妇女两年中血清铜的变化,此外对6名正常妇女及6名置Cu-T_(200)开始1个月的妇女每周2次测定血清铜含量共1个月以研
The authors studied serum copper levels in women who had been using Cu-IUD for a long period of time to determine if any change in copper levels associated with long-term use of Cu-IUD was associated with copper poisoning. The cross-sectional study included 148 women without any birth control method (control group), 95 women aged 6 to 48 months with Lippes Loop, and 107 women aged 6 to 48 with Cu-T 200 Months of women’s serum copper levels were determined to determine whether there was any difference in serum copper levels between Cu-IUD and non-users. Longitudinal studies included 7 women without any birth control method and 17 women with Cu-IUD who measured serum copper levels every 3 months for up to 24 months to follow up on Cu-IUD and Cu -IUD changes in serum copper in two years of women, in addition to six normal women and six women set Cu-T 200 (200) at the beginning of a month 2 times a week to determine the serum copper content of 1 month to study