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目的评价伴中央-颞部棘波良性儿童癫痫间(BECTS)患儿是否存在认知损害,以及认知、临床和脑电图、P300、失匹配负波(MMN)之间的关系。方法通过收集临床资料、行韦氏儿童智力量表测验、24h动态脑电图及P300和失匹配负波检查,分析其关系。结果 BECTS患儿的总智商在正常范围,但言语智商受到不同程度损害;其中知识、分类和词汇能力受损明显;发病年龄越早,越易发生认知功能损害。结论失匹配负波可能作为一种评价BECTS患儿认知损害的客观指标。
Objective To evaluate whether there is cognitive impairment in children with central-temporal spine wave benign childhood epilepsy (BECTS) and the relationship between cognitive, clinical and electroencephalogram (P300), mismatched negative (MMN). Methods The clinical data were collected and the Wechsler Children’s Intelligence Scale Test, 24-hour dynamic electroencephalogram and P300 and mismatch negative-tone test were used to analyze the relationship. Results The total IQ of children with BECTS was within the normal range, but the speech IQ was impaired to varying degrees. Among them, the knowledge, classification and vocabulary ability were significantly impaired. The earlier the age of onset, the more likely cognitive impairment occurred. Conclusion Mismatch negative waves may be used as an objective evaluation of cognitive impairment in children with BECTS.