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20余年来急性中耳炎的治疗发生了很大变化。以前肌肉注射抗生素治疗应用很普遍,但现在很大程度上已不再应用而推崇口服抗生素治疗。近来的研究表明,口服疗程缩短至2～3天不影响疗效。另外还有学者指出,应用抗生素治疗急性中耳炎毫无实效,并可能促使出现慢性中耳渗液。因此Mygind等(1981)主张摒弃应用抗生素治疗中耳炎。作者取自急性中耳炎小儿中耳分离出的流感嗜血杆菌造成栗鼠急性中耳炎模型,经适当的和不适当的抗生素治疗观察中耳炎渗液的发展。另以注射用水注入正常耳观察其清除情
More than 20 years of treatment of acute otitis media have undergone great changes. Previous antibiotic treatment of intramuscular injection of the application is very common, but is now largely unsuccessful and respected oral antibiotic therapy. Recent studies have shown that shortening oral treatment to 2 to 3 days does not affect the efficacy. In addition there are scholars pointed out that the application of antibiotics in the treatment of acute otitis media ineffective, and may prompt the emergence of chronic middle ear effusion. Therefore, Mygind et al. (1981) advocated the abandonment of the application of antibiotics to treat otitis media. The author was isolated from the middle ear of children with acute otitis media Haemophilus influenzae caused chinchilla acute otitis model, with appropriate and inappropriate antibiotic treatment to observe the development of otitis media exudate. The other injection of water into the normal ear to observe the removal of emotion