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焦磷酸根(PPi)作为一种重要的生物功能阴离子在生命科学、环境科学、药物领域和化学过程等方面起着非常重要的作用.鉴于荧光分析具有操作简便、灵敏度高等突出优点,设计合成高效的PPi荧光探针成为近年来超分子化学研究的热点之一.综述了近年来PPi荧光识别与传感的多种设计策略与原理,主要包括基于荧光增强或淬灭型识别,激基缔合物识别,荧光指示剂置换,静电或氢键作用识别等.DPA-金属离子络合物,尤其是DPA-Zn2+络合物,作为识别基团对PPi有着显著的亲和性和选择性识别能力.DPA-Zn2+络合物与多种荧光团或者荧光指示剂组合而形成的化学传感体系已经被广泛应用于PPi荧光识别与传感.
As an important biofunctional anion, pyrophosphate (PPi) plays a very important role in life sciences, environmental sciences, pharmaceuticals and chemical processes, etc. In view of the advantages of simple operation and high sensitivity, fluorescence analysis has been designed and synthesized PPi fluorescent probe has become one of the hot spots in the field of supramolecular chemistry.In recent years, many design strategies and principles of fluorescence recognition and sensing of PPi are summarized, including fluorescence-based or quenching-based recognition, Substance recognition, fluorescent indicator replacement, electrostatic or hydrogen bond recognition, etc. DPA-metal ion complexes, especially DPA-Zn2 + complexes, have significant affinity and selectivity for PPi as recognition groups Chemical sensing systems formed by the combination of DPA-Zn2 + complexes with various fluorophores or fluorescent indicators have been widely used in PPi fluorescence recognition and sensing.