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目的：探讨应用恩丹西酮、氟哌利多预防术后恶心、呕吐的效果。方法：按美国麻醉协会分级（ＡＳＡ）Ⅰ～Ⅱ级择期全子宫切除６０例，随机分为三组：Ａ组，静脉注射１０ｍｌ生理盐水；Ｂ组，静脉注射恩丹西酮４ｍｌ和生理盐水１０ｍｌ；Ｃ组，静脉注射氟哌利多２．５ｍｇ和生理盐水１０ｍｌ，观察各组术后２４ｈ内恶心的程度和呕吐次数，同时记录副作用。结果：Ａ组患者恶心、呕吐发生率均高于Ｂ组和Ｃ组（Ｐ＜０．０１），而Ｂ组和Ｃ组差异无显著性（Ｐ＞０．０５）。三组均无明显的副作用。结论：恩丹西酮和氟哌利多对全子宫切除术后均有良好的预防恶心、呕吐的作用
Objective: To investigate the effect of ondansetron and droperidol in preventing postoperative nausea and vomiting. Methods: Sixty ASA Ⅰ ~ Ⅱ total hysterectomy patients were randomly divided into three groups: group A, intravenous injection of 10ml normal saline; group B, intravenous ondansetron 4ml and saline 10ml . In group C, 2.5 mg of droperidol and 10 ml of saline were intravenously injected. The degree of nausea and the number of vomiting were observed within 24 hours after operation and the side effects were recorded. Results: The incidence of nausea and vomiting in group A was higher than that in groups B and C (P <0.01), but there was no significant difference between groups B and C (P> 0.05). Three groups had no obvious side effects. Conclusion: Ondansetron and droperidol have a good effect in preventing nausea and vomiting after total hysterectomy