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目的了解云南省鲁甸县健康人群麻疹抗体水平,为制定麻疹防控措施提供科学依据。方法采用分层整群抽样方法于2016年6月抽取344名8月龄-45岁健康人群作为调查对象,采用酶联免疫吸附试验检测调查对象血清麻疹Ig G抗体。结果 344名调查对象的麻疹抗体阳性率为92.73%,抗体保护率为77.33%,几何平均浓度(Geometric mean concentration,GMC)为1 160.51m IU/ml。Logistic回归分析显示,地区是麻疹抗体阳性率的影响因素;年龄、民族、地区是麻疹抗体保护率的影响因素。结论鲁甸县健康人群麻疹抗体维持在高水平,应在人群麻疹抗体水平较低地区开展含麻疹成分疫苗的补充免疫。
Objective To understand the level of measles antibody in healthy population in Ludian County, Yunnan Province, and to provide a scientific basis for the development of measles prevention and control measures. Methods A stratified cluster sampling method was used to collect 344 healthy people aged from 8 months to 45 years in June 2016 as the survey subjects. Serum measles Ig G antibody was detected by enzyme linked immunosorbent assay (ELISA). Results The positive rate of measles antibody in 344 subjects was 92.73%, the antibody protection rate was 77.33%, and the geometric mean concentration (GMC) was 1 160.51m IU / ml. Logistic regression analysis showed that the area was the influencing factor of measles antibody positive rate. Age, nationality and region were the influencing factors of measles antibody protection rate. Conclusion The measles antibody in healthy population in Ludian County should be maintained at a high level. Supplementary immunization with measles vaccine should be carried out in areas with low population of measles antibody.