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目的了解导致成都市婴幼儿腹泻疾病的主要病原微生物,获得成都市地区婴幼儿腹泻病原谱,为预防控制疾病提供参考依据。方法对成都市儿童医院<5岁婴幼儿门诊和住院腹泻患儿采集粪便样本,并对样本进行10种细菌、7种病毒和3种寄生虫检测。结果共采集433份腹泻患者粪便标本,共检出各类腹泻病原微生物337株,总检出率为77.83%。其中肠道致病细菌30株,检出率6.93%,腹泻病毒305份,检出率70.44%,寄生虫2份,检出率0.46%。肠道致病细菌中沙门菌最多(25株,6.89%)。腹泻病毒中A组轮状病毒130份,占38.58%;其次为杯状病毒最多(109份),占32.34%,结论成都市<5岁婴幼儿感染性腹泻病例主要集中在0～1岁年龄组,引起成都市婴幼儿腹泻的病原微生物以腹泻病毒和肠道致病菌为主,其中杯状病毒、A组轮状病毒和沙门菌为主要病原微生物。
Objective To understand the major pathogenic microorganisms that cause diarrhea in infants and young children in Chengdu and to get the pedigree of diarrhea in infants and young children in Chengdu area, so as to provide reference for prevention and control of diseases. Methods Stool samples were collected from pediatric outpatients and hospitalized children with diarrhea in Chengdu Children’s Hospital <5 years old, and the samples were tested for 10 kinds of bacteria, 7 kinds of viruses and 3 kinds of parasites. Results A total of 433 diarrhea patients stool samples were collected, a total of 337 pathogenic microorganisms were detected, the total detection rate was 77.83%. Including intestinal bacteria 30 strains, the detection rate of 6.93%, 305 copies of diarrhea virus, the detection rate was 70.44%, 2 parasites, the detection rate of 0.46%. Salmonella in enteropathogenic bacteria was the most (25 strains, 6.89%). In the diarrhea virus, 130 cases were group A rotavirus, accounting for 38.58%; followed by calicivirus (109 cases), accounting for 32.34%. Conclusion The cases of infantile infectious diarrhea <5 years old in Chengdu mainly concentrated in the age of 0-1 Group, the cause of diarrhea in infants and young children in Chengdu pathogenic microorganisms to diarrhea and enteric pathogens, including cup virus, rotavirus group A and Salmonella as the main pathogenic microorganisms.