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观察 41例急性心肌梗死患者发病当日及发病第 3,7,14d血浆内皮素 (ET 1)、心房利尿肽 (ANP)、血清胰岛素浓度以及血清脂质水平。结果表明 :心肌梗死急性期血脂呈现以总胆固醇 (TC)与低密度脂蛋白胆固醇 (LDL C)降低、甘油三酯 (TG)升高为主的动态性改变 ;同时 ,内分泌因子ET 1,ANP和胰岛素也呈现动态性变化 ,并可能通过某些细胞因子影响血脂代谢。提示心肌梗死急性血脂呈特征性动态变化 ,对心肌梗死二级预防具有重要意义。
The plasma endothelin (ET 1), atrial natriuretic peptide (ANP), serum insulin concentration and serum lipid level were observed on the onset day and on the 3rd, 7th and 14th day in 41 patients with acute myocardial infarction. The results showed that: the acute phase of myocardial infarction showed a change of total cholesterol (TC) and low density lipoprotein cholesterol (LDL C), triglyceride (TG) mainly dynamic changes; the same time, endocrine factor ET 1, ANP And insulin also showed dynamic changes, and may affect blood lipid metabolism through certain cytokines. Tip acute myocardial infarction showed characteristic dynamic changes in secondary prevention of myocardial infarction is of great significance.