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膀胱引流期间接受抗生素的患者较未接受者尿路感染发生率为低,然而由于担心产生抗药菌株而不甚赞成对尿道插管者使用抗生索预防感染。作者在一组术后拟进行3～14天膀胱引流的手术患者中,开展了一项预防性使用环丙沙星的以安慰剂对照的双盲研究。患者随机分为安慰剂组(61例)、250mg/日环丙沙星组(59例)和500mg/每日2次环丙沙星组(64例)。各组均于术后第2天起投药,直
Patients who received antibiotics during bladder drainage had a lower prevalence of urinary tract infections than non-recipients, but were less likely to favor the use of antibiotic cables for urethral intubation to prevent infection due to fears of producing resistant strains. The authors undertook a placebo-controlled, double-blind study of prophylactic ciprofloxacin in a group of patients who underwent bladder drainage for 3 to 14 days postoperatively. Patients were randomized to placebo (61), ciprofloxacin 250 mg daily (n = 59) and ciprofloxacin 500 mg twice daily (n = 64). Each group was administered the first 2 days after surgery, straight