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为了观察膀胱癌患者红细胞免疫功能的变化状况，对41例膀胱癌患者（观察组）红细胞免疫功能和血清循环免疫复合物进行检测，并且与55例健康对照组进行比较。结果观察组红细胞C3b受体花环率（RCR）明显低于健康对照组，而红细胞免疫复合物花环率（RCIR）明显增高，血清循环免疫复合物（CIC）含量亦明显高于健康对照组（均P＜0．01）。T1－2期膀胱癌患者RCR水平低于T3－4期膀胱癌患者，而RICR水平则明显高于T3－4期膀胱瘤患者（P＜0．01），CIC含量相应增高（P＜0．05）。膀胱肿瘤切除后RIR升高，RICR降低（P＜0．01）。膀胱癌术后无复发者RCR和RLCR水平及CIC含量与健康对照组无显著性差异（均P＞0．05）；复发者RCR水平明显低于无复发者和健康对照组，而RCIR水平和CIC含量则明显高于无复发者和健康对照组（均P＜0．01）。提示膀胱癌患者红细胞免疫功能降低，血清CIC含量增加；随着肿瘤负荷的减少，机体红细胞免疫功能可逐渐恢复。认为检测膀胱癌患者红细胞免疫功能对疾病诊断、病情估计和预后判断具有一定的意义。
In order to observe the changes of erythrocyte immune function in bladder cancer patients, the immune function of erythrocyte in 41 bladder cancer patients (observation group) and serum immune complexes were detected and compared with 55 healthy controls. Results The rosette rate of erythrocyte C3b receptor (RCR) in observation group was significantly lower than that of healthy control group, but the RCIR of erythrocyte immune complex was significantly increased, and the content of circulating immune complex (CIC) was also significantly higher than that of healthy control group P <0.01). Patients with T1-2 bladder cancer had lower RCR levels than those with T3-4 bladder cancer, while RICR levels were significantly higher than those with T3-4 bladder cancer (P <0.01) and CIC levels (P <0. 05). RIR increased and RICR decreased after bladder tumor resection (P <0.01). There was no significant difference in RCR and RLCR levels and CIC levels between the two groups (all P> 0.05). The RCR level of the relapsed patients was significantly lower than that of the non-recurrence and healthy controls CIC content was significantly higher than those without recurrence and healthy control group (P <0.01). Prompted that patients with bladder cancer decreased erythrocyte immune function, serum CIC content increased; with the reduction of tumor burden, the body’s immune function of red blood cells can be gradually restored. That the detection of bladder cancer in patients with erythrocyte immune function diagnosis of the disease, disease estimation and prognosis have some significance.