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目的探讨安神补心丸辅助治疗顽固性失眠的临床效果。方法选取2010年3月至2013年3月80例顽固性失眠患者,随机分观察组和对照组。对照组40例,予常规西医治疗,观察组40例,在对照组基础上加用安神补心丸辅助治疗,连续治疗4周,观察治疗后相关指标变化。结果两组治疗前睡眠质量、入睡时间、睡眠时间、睡眠效率、睡眠障碍评分比较差异无统计学意义(P>0.05),两组治疗后睡眠质量、入睡时间、睡眠时间、睡眠效率、睡眠障碍评分均低于治疗前(P<0.05),且治疗后观察组各评分均低于对照组(P<0.05);观察组治疗后在催眠药物使用频次、催眠药物使用总剂量、并发症发生率、治疗时间上明显少于对照组(P<0.05)。观察组治疗总有效率为92.5%,高于对照组治疗总有效率为80%(P<0.05)。结论在常规西医治疗的基础上合并安神补心丸,能更有效的改善顽固性失眠的临床效果。
Objective To investigate the clinical effect of Anshen Buxin pills in treating stubborn insomnia. Methods From March 2010 to March 2013, 80 patients with refractory insomnia were randomly divided into observation group and control group. Control group of 40 cases, conventional Western medicine treatment, observation group 40 cases, on the basis of the control group with Anshen Buxin Pill adjuvant therapy, continuous treatment for 4 weeks to observe the change of relevant indicators after treatment. Results There were no significant differences in sleep quality, sleep time, sleep time, sleep efficiency and sleep disturbance score between the two groups before treatment (P> 0.05). The quality of sleep, sleep time, sleep time, sleep efficiency, sleep disturbance (P <0.05). After treatment, the scores in the observation group were lower than those in the control group (P <0.05). The frequency of hypnotic drug use, the total dosage of hypnotic drugs, the incidence of complications , The treatment time was significantly less than the control group (P <0.05). The observation group, the total effective rate was 92.5%, higher than the control group, the total effective rate was 80% (P <0.05). Conclusion Combination of Anshen Bu Xin Wan on the basis of conventional Western medical treatment can more effectively improve the clinical effect of refractory insomnia.