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测定了５４例冠心病患者（心绞痛３３例、急性心肌梗塞２１例）的唾液溶菌酶、ＳＩｇＡ、ＩｇＡ、ＩｇＧ４项指标，并与６３例正常人唾液标本进行对照。心绞痛和急性心肌梗塞患者的唾液溶菌酶显著低于正常人（Ｐ＜０．０００１），ＳＩｇＡ、ＩｇＡ、ＩｇＧ水平则明显高于正常人（Ｐ＜０．０００１），心绞痛与急性心肌梗塞的ＳＩｇＡ含量差异亦有显著性（Ｐ＜０．０１）。初步显示检测唾液免疫指标，对冠心病的病理生理研究有一定的临床意义。
Salivary lysozyme, SIgA, IgA and IgG4 indicators of 54 patients with coronary heart disease (33 cases of angina pectoris and 21 cases of acute myocardial infarction) were measured and compared with 63 normal human saliva samples. Salivary lysozyme was significantly lower in patients with angina pectoris and acute myocardial infarction than those in normal controls (P <0.0001). SIgA, IgA and IgG levels were significantly higher in patients with angina pectoris and acute myocardial infarction than in controls (P <0.0001) The difference was also significant (P <0.01). The preliminary detection of saliva immune indicators, the pathophysiology of coronary heart disease has some clinical significance.