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目的分析住院的老年潜伏梅毒患者临床特征和血清学特点,为防治该类疾病提供科学依据。方法回顾性分析2009年1月-2012年12月本院106例住院的老年潜伏梅毒患者的临床资料,包括术前、有创检查前及输血前筛查等进行梅毒血清学试验结果,并对其性别、病因、住院科室、夫妻双方血清学试验结果进行统计学分析。结果 106例老年潜伏梅毒住院患者中,男44例,女62例,脑脊液检查结果均为阴性。25.47%(27/106)患者有非婚性接触史,且4年来,该类患者病例数呈逐年增多趋势。共分布于全院24个科室,普通外科14例(13.21%),泌尿外科13例(12.26%),妇科9例(8.49%)。其RPR滴度均较低(≤1∶8者104例,占98.11%)。经规范驱梅治疗半年后血清转阴率偏低6.60%(7/106),出现血清固定65.09%(69/106)。结论住院的老年潜伏梅毒患者有逐年增多的趋势,而且规范驱梅治疗后血清固定发生率较高。该类患者可分布于全院各科室,以普通外科居多。
Objective To analyze the clinical characteristics and serological features of elderly latent syphilis in hospital and provide a scientific basis for the prevention and treatment of such diseases. Methods The clinical data of 106 elderly hospitalized latent syphilis patients in our hospital from January 2009 to December 2012 were retrospectively analyzed. Results of pre-and post-transfusion screening and pre-transfusion screening were included in this study. The gender, etiology, hospital department, husband and wife serological test results for statistical analysis. Results Among the 106 elderly patients with latent syphilis hospitalization, 44 were male and 62 were female, and the results of cerebrospinal fluid examination were negative. 25.47% (27/106) patients had a history of non-marital contact, and in 4 years, the number of cases of such patients showed an increasing trend year by year. There were 14 departments (13.21%) in general surgery, 13 cases (12.26%) in urology and 9 cases (8.49%) in gynecology. The RPR titers were low (≤ 1: 8 in 104 cases, accounting for 98.11%). Six months after the standard treatment of plum, the serum negative conversion rate was 6.60% (7/106), with a serum fixation rate of 65.09% (69/106). Conclusions The number of elderly latent syphilis patients in hospital tends to increase year by year, and the incidence of serum fixation is higher after standardizing the treatment of plum. Such patients can be located in various departments of the hospital, mostly in general surgery.