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本院自1982～1992年共收治20例直肠癌中发现一家三代4人同患直肠癌,报道如下。例1,女,42岁。主因腹泻半年,经治不愈来院就治。半年来腹泻时好时犯,有时大便带粘液,近2个月来大便带血,量不多,曾多次以肠炎、痢疾口服地霉素、四环素、卡那霉素、黄连素等药治疗无效。直肠指诊,直肠粘膜处触到2cm×3cm×3cm大小肿块,指套带有粘液。乙状结肠镜检查:在直肠与乙状结肠交界处有2.5cm×3cm×3cm结节状肿物,表面有溃疡,触之出血。诊断:直肠癌。后转北京医院手术治疗。病理诊断:直肠腺癌。
In this hospital, from 1982 to 1992, a total of 20 cases of rectal cancer were treated, and a family of 3 people with 4 cases of rectal cancer was found. The report is as follows. Example 1, female, 42 years old. The main cause was diarrhea for half a year. In the past six months, when diarrhea was committed in a good time, sometimes with mucous stool, stool blood in the past 2 months, the amount is small, has repeatedly treated with enteritis, dysentery oral tetracycline, tetracycline, kanamycin, berberine and other drugs invalid. Rectal examination, rectal mucosa touched 2cm × 3cm × 3cm size lump, fingertips with mucus. Sigmoidoscopy: There was a 2.5cm × 3cm × 3cm nodular mass at the junction of the rectum and sigmoid colon, with ulcers on the surface and bleeding from the touch. Diagnosis: rectal cancer. After the transfer to Beijing hospital surgery. Pathological diagnosis: rectal adenocarcinoma.