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The paper presents modelling and simulation of a local blast wave interaction with a tire of a logistic truck supporting military operations. In the military industry, it is desired to improve effectiveness and strength of vehicle components and simultaneously to minimize the risk of crew injuries. Therefore, the main goal of this paper is to present an attempt to improve blast resistance of a tire. Based on the developed, verified and validated finite element model an optimization procedure was conducted to minimize the damage of a tire subjected to a blast wave. The main issue in the performed computations was to estimate an influence of the cords angle in each layer. For this purpose, a pre-processor script was developed in order to easily modify the finite element model so that the generation process was per-formed automatically on the basis of optimization variables. Dynamic response of a tire subjected to blast wave in different cases (cords configurations) was analyzed. It was shown that the optimized cords angles configuration reduces tire local damage and increases its blast resistance.