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患者26岁,G_1P_1,于1997年3月16日(月经后第4天)在乡计划生育服务站放置含铜宫内节育器(IUD)避孕。术前检查一般情况好,无手术禁忌症。手术顺利无不适感,未给予任何服用药。6小时后全身皮肤逐渐出现大小不等红色斑疹,以躯干、四肢为多,对称分布,搔痒难忍,伴有畏寒、发热、恶心、呕吐等症状。患者立即就诊,被疑为铜过敏,取器并给予补液、抗过敏及对症治疗。术后第4天时全身症状逐渐缓解,但皮肤斑疹融合成大片,并出现广泛潮红、肿胀,以腋窝、腹股沟等皮肤皱摺部为重。术后第10天肿胀消退,皮肤呈叶状或小片鳞状大块剥脱,仍以皱褶部皮肤为重,并反复脱屑。于术后第12天转我站就诊。患者既往体健,有磺胺药过敏史,但此次发病前2周无任何口服或外用药史,既往
The patient, age 26, G_1P_1, placed a copper-containing intrauterine device (IUD) contraception at a township family planning service station on March 16, 1997 (the fourth day after menstruation). Preoperative examination is generally good, no surgical contraindications. Surgery without any discomfort, did not give any medication. After 6 hours, the skin of the whole body gradually appeared red-spotted with sizes varying from the trunk to the extremities, with symmetrical distribution and itching, with symptoms such as chills, fever, nausea and vomiting. Patients immediately treated, was suspected of copper allergy, take and give rehydration, anti-allergy and symptomatic treatment. Systemic symptoms gradually eased on the 4th postoperative day, but the skin spots were fused into large patches with widespread flushing and swollenness, with the emphasis on the skin folds, such as the armpits and the groin. On the 10th day after operation, the swelling subsided, and the skin showed leaf-like or small scaly massive exfoliation. The skin of the folds was still heavy, and repeated desquamation. On the 12th day after my turn to the doctor. Past physical health of patients with allergies to sulfa drugs, but no 2 weeks before the onset of any oral or external medication history, past