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目的探讨非小细胞肺癌(NSCLC)化疗患者抑郁状况并分析其影响因素,为临床护理NSCLC化疗患者提供科学的理论依据。方法 2015年1-6月,采用自行设计的一般状况调查表、抑郁自评量表(SDS)、社会支持评定量表(SSRS)和视觉模拟疼痛评分量表,对上海市肺科医院104例住院的NSCLC化疗患者进行问卷调查,对患者的抑郁状况、疼痛、社会支持水平、患者的基线资料进行相关性及多元逐步回归统计分析。结果 NSCLC化疗患者抑郁评分显著高于国内正常人群[分别为(38.15±9.44)和(33.46±8.50)分],社会支持总分、客观支持分和对支持的利用度评分[分别为(38.88±8.92)、(8.54±2.18)和(7.42±2.46)分]显著低于国内正常人群[分别为(44.38±8.38)、(12.68±3.47)和(9.38±2.40)分],差异均有统计学意义(P<0.01)。104例患者中,16例患者存在抑郁症状,占15.38%。32例处于高水平社会支持,64例处于中等水平社会支持,8例处于低水平社会支持。影响非小细胞肺癌化疗患者抑郁的主要因素是疼痛评分、化疗次数、年龄、文化程度、婚姻状况和主观支持水平,均有统计学意义(P<0.05,P<0.01)。结论有效的社会支持对减轻NSCLC化疗患者抑郁症状有积极作用。护理患者时,应根据其疼痛评分、化疗次数、年龄、文化程度、婚姻状况和主观支持水平采取针对性的干预措施。
Objective To investigate the status of depression in patients with non-small cell lung cancer (NSCLC) chemotherapy and analyze its influencing factors to provide a scientific basis for clinical nursing of patients with NSCLC. Methods From January to June 2015, self-designed questionnaires of general condition, self-rating depression scale (SDS), social support rating scale (SSRS) and visual analogue pain rating scale were used to analyze 104 cases of Shanghai Pulmonary Hospital Hospitalized patients with NSCLC chemotherapy were surveyed, and their correlations and multiple stepwise regression were statistically analyzed for depression, pain, social support, and baseline data. Results The scores of depression in patients with NSCLC were significantly higher than those in the normal population [(38.15 ± 9.44) and (33.46 ± 8.50), respectively], social support score, objective support score and supportive support score [38.88 ± 8.92), (8.54 ± 2.18) and (7.42 ± 2.46), respectively, were significantly lower than those in the normal population [(44.38 ± 8.38), (12.68 ± 3.47) and (9.38 ± 2.40) Significance (P <0.01). Among the 104 patients, 16 patients had depressive symptoms, accounting for 15.38%. 32 cases were at high levels of social support, 64 cases were at medium level of social support, and 8 cases were at low levels of social support. The main factors influencing depression in NSCLC patients were pain score, number of chemotherapy, age, education, marital status and subjective support (P <0.05, P <0.01). Conclusion Effective social support has a positive effect on the reduction of depressive symptoms in NSCLC patients undergoing chemotherapy. When nursing a patient, targeted interventions should be based on their pain score, frequency of chemotherapy, age, education, marital status, and subjective support.