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为探讨母乳喂养与乙型肝炎病毒携带关系，对筛选出的１４５ 例 Ｈ Ｂｓ Ａｇ 阳性产妇应用酶联免疫法及 Ｐ Ｃ Ｒ 技术分别检测母血、乳汁、脐血及婴儿血 Ｈ Ｂ Ｖ５ 项标志物及 Ｈ Ｂ Ｖ Ｄ Ｎ Ａ。结果： Ｈ Ｂ Ｖ标志物阳性率与 Ｈ Ｂ Ｖ Ｄ Ｎ Ａ 阳性率相关；母乳喂养后婴儿血 Ｈ Ｂ Ｖ 携带率比未母乳喂养时脐血 Ｈ Ｂ Ｖ携带率低，而且母乳喂养对有免疫防护的婴儿不会增加乙肝病毒的感染机会，反而母乳喂养后婴儿 Ｈ Ｂ Ｖ 携带率较母乳喂养前有下降趋势；应用乙肝免疫球蛋白于孕中期起注射，发现其初乳、脐血、婴儿血 Ｈ Ｂ Ｖ 携带率均有下降趋势，显示出这种免疫阻断法对降低新生儿 Ｈ Ｂｓ Ａｇ 携带状态具有新的临床价值。
To investigate the relationship between breastfeeding and hepatitis B virus infection, 145 HbsAg-positive mothers were screened for Hb V5 markers using maternal blood, milk, umbilical cord blood and infants by enzyme-linked immunosorbent assay (ELISA) and P C R And H B V D N A. Results: The positive rate of H B V marker was correlated with the positive rate of H B V D N A; the carrier rate of H B V in infants after breastfeeding was lower than that of H B V in umbilical blood without breastfeeding, Immune protection of infants did not increase the chances of hepatitis B infection, but after breastfeeding babies H B V carrier rate than before breast-feeding has a downward trend; application of hepatitis B immunoglobulin in the second trimester injection and found that colostrum, umbilical cord blood, Hb V carrier rate of infant blood has a downward trend, showing that this method of blocking immunosuppression in neonatal H Bs Ag carrying a new clinical value.