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动脉粥样硬化损害分布与动脉开口、分支有关。对39例尸体腹主动脉分叉处粥样斑分布进行观察及对7例左、右髂总动脉(有斑块)作1mm厚的连续横切,通过微机进行统计分析,发现左、右髂总动脉内斑块分布,均以分叉的内侧壁面为多。左、右侧分别占病变例数90％、93％。在病变血管中可见管壁内侧增厚的新月型斑块。从流体力学分叉管处的速度剖面可知,分叉管内侧壁面切应力高于外侧。这与粥样斑形成的高切应力理论相吻合。高切应力对内皮的损伤可看作是早期粥样斑块形成的始动因素之一。
The distribution of atherosclerotic lesions is related to arterial openings and branches. 39 cases of cadaveric aorta bifurcation atherosclerotic plaque distribution observed in 7 cases of left and right common iliac artery (plaque) for 1mm thick continuous transection, through the statistical analysis of the computer and found that the left and right iliac The distribution of plaques in the common arteries are mostly bifurcated medial wall. Left and right lesions accounted for 90% of cases, 93%. In diseased vessels, thickening of the crescent-shaped plaque appears on the medial wall of the vessel. From the velocity profile of the bifurcation of hydrodynamics, the shear stress of the inner wall of the bifurcated tube is higher than that of the outer side. This coincides with the theory of high shear stress induced by atheroma formation. High shear stress on the endothelium damage can be seen as one of the initiating factors of early atherosclerotic plaque formation.