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目的探讨不同地区和不同民族12个群体15个STR基因座的遗传关系研究。方法通过收集不同地区和不同民族12个群体的D5S818、D7S820、D8S1179、D13S317、D16S539、D18S51、D19S433、D21S11、FGA、TH01、TPOX、v WA、CSF1PO、D2S1338、D3S1358基因座的基因频率资料,计算他们间的遗传距离,构建系统发生树。结果山东、吉林、甘肃汉族人群与北方汉族聚为一类。吉林汉族、山东汉族、甘肃汉族、北方汉族、西北地区汉族、河南汉族聚为一大类。结论研究结果与遗传学和民族学研究结果一致,并提示本研究所涉及人群的STR基因频率分布与地理距离呈平行关系。
Objective To investigate the genetic relationship of 15 STR loci in 12 populations from different regions and ethnic groups. Methods The frequencies of D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D19S433, D21S11, FGA, TH01, TPOX, v WA, CSF1PO, D2S1338 and D3S1358 loci in 12 populations from different regions and ethnicities were calculated. The genetic distance between them, building a phylogenetic tree. The results of Shandong, Jilin, Gansu Han and North Han nationality as a group. Han nationality in Jilin, Han nationality in Shandong, Han nationality in Gansu, Han nationality in the north, Han nationality in the northwest region and Han nationality in Henan province. Conclusions The findings are in agreement with the results of genetics and ethnology studies and suggest that the frequency distribution of STR genes in this population is parallel to the geographical distance.