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近15年来化疗对卵巢上皮性肿瘤起着日益重要的作用。由于卵巢癌在腹腔内的隐蔽性,仍使在疾病的监护上存在一些困难。第二次探查(Second Look)对估价化疗作用及指导以后的治疗有一定价值,若发现仍有肿瘤则须进一步治疗,而使延长化疗者增多,估计约10%的病人接受长期化疗。这些病人在临床上并无肿瘤存在的表现。长时间化疗的合并症近年日趋增多,主要是对骨髓的毒性,表现为两种严重的并发症:慢性白细胞或血小板减少症及白血病。为了解那些冒着一定危险继续化疗患者的肿瘤情况以决
Chemotherapy has played an increasingly important role in ovarian epithelial tumors in the past 15 years. Owing to the hidden nature of ovarian cancer in the abdominal cavity, there are still some difficulties in the monitoring of the disease. Second Look has some value in assessing the effects of chemotherapy and in guiding future treatments. If tumors are found, further treatment is needed, leading to an increase in prolonged chemotherapy, and about 10% of patients are estimated to receive long-term chemotherapy. These patients are clinically tumor-free. Prolonged chemotherapy complications have been increasing in recent years, mainly on the toxicity of bone marrow, manifested as two serious complications: chronic leukopenia or thrombocytopenia and leukemia. To understand those who run the risk of continuing chemotherapy in patients with cancer to decide