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目的 调查肝癌病人生存质量情况和影响因素。方法 采用消化病生存质量指数(GLQI指数 )前瞻性地测定 36例肝癌病人在术前至术后 2年内不同时期的生存质量值。结果 术前平均GLQI指数为 (10 6± 13)分 ,术后 2～ 10周GLQI指数明显下降 (P <0 .0 5～ 0 .0 1) ,第 4个月接近术前水平 (P >0 .0 5 ) ,第 9个月达 (115± 11)分 ,超过术前水平 (P =0 .0 2 )。在术后较早期 ,老年组较非老年组、术前肝功能ChildB级组较A级组、联合肝段和半肝切除较肝段切除组生存质量降幅更大 (P <0 0 5 )。肿瘤复发病人生存质量持续下降 (P <0 .0 5～ 0 .0 0 1)。结论 生存质量测定可有效地用于肝癌病人的健康和疗效评估。肿瘤复发、肝功能障碍、年龄和手术创伤是影响生存质量的主要因素
Objective To investigate the quality of life and influencing factors of liver cancer patients. Methods The quality of life of 36 patients with hepatocellular carcinoma was determined prospectively using the digestive disease quality of life index (GLQI index) from preoperative to postoperative 2 years. Results The average preoperative GLQI index was (10 6 ± 13) points. The GLQI index decreased significantly from 2 to 10 weeks after surgery (P 0.05-0.01). The 4th month was close to the preoperative level (P > 0. 0 5), reached (115 ± 11) points in the 9th month, exceeding the preoperative level (P = 0.02). At the early postoperative period, the quality of life of the elderly group was significantly lower than that of the non-elderly group, and the preoperative liver function was significantly lower in the Child B group than in the A group, combined hepatectomy, and hepatectomy (P < 0.05). The quality of life of patients with recurrent tumors continued to decline (P < 0.05 to 0.001). Conclusion The quality of life measurement can be effectively used to assess the health and efficacy of liver cancer patients. Tumor recurrence, liver dysfunction, age and surgical trauma are the main factors affecting quality of life