Phenylacetylglutaminate and Phenylacetate in Combination Upregulate VDUP1, Cause Cell Cycle Blockade

• 作 者: Sonali S. Patil Stanislaw R. B
• 机 构: CenterforFunctionalGenomics,DepartmentCellandMolecularBiology
• 出 处: 癌症治疗(英文)
• 发表日期: 2012年3期
• 关键词: GLIOBLASTOMA VDUP1 Phenylacetylglutaminate PHENYLACETATE APOPTOSIS Drug COMBINAT

Phenylacetylglutaminate (PG) and Phenylacetate (PN) are metabolites of Phenylbutyrate (PB) and are constituents of antineoplaston AS2-1. These are sodium salts of amino acid derivative and carboxylic acid that inhibit the growth of neoplastic cells withou